《應用毒理學雜志》致力于在分子細胞組織和靶器官水平上發表有關藥物和化學品對生物系統毒性的原始研究理論和文獻綜述。這也包括致畸、致癌、突變、機械技術、藥代動力學、環境毒理學和環境衛生（包括流行病學研究）以及分析和方法開發研究。鼓勵發表有關體外技術和動物使用替代方法的論文。動物實驗應符合現行的國家或國際動物福利護理和處理標準（如NUH指南）。對人體志愿者和患者的調查必須表明，已經遵循了相關的倫理審查和指導方針，包括獲得知情權。論文必須具有明確的科學價值，有助于毒理學的知識和進步。所有的論文都將被獨立引用。稿件必須用英語書寫，除作為科學會議的摘要外，不得在其他地方發表。將發表評論文章，并重新征求其中一位編輯的意見。評論文章也將被引用。作者必須同意不將同一材料傳播到其他地方出版。

The Journal of Applied Toxicology is devoted to publishing original research theoretical and literature reviews relating to the toxicity of drugs and chemicals to living systems at the molecular cellular tissue and target organ level. This also encompasses teratogenesis carcinogenesis mutagenesis mechanistic technology pharmacokinetics environmental toxicology and environmental health (including epidemiological studies) in addition to analytical and method development studies. Papers dealing with in vitro techniques and alternatives to the use of animals are encouraged. Experiments on animals should conform to prevailing national or international standards of welfare care and handling of animals (eg NUH guidelines). Investigations in human volunteers and patients must indicate that relevant ethical reviews and guidelines have been followed including obtaining informed consent. Papers must be of clear scientific value and contribute to knowledge and advancement in toxicology. All papers will be independently refereed. Contributions must be in English and not have been published elsewhere except as abstracts at scientific meetings. Review articles will be published and prior consultation with one of the editors is reommended. Review articles will also be refereed. Authors must agree not to communicate the same material for publication elsewhere.