該雜志及時(shí)發(fā)表與醫(yī)學(xué)研究相關(guān)的評(píng)論，廣泛定義了作者已作出重大貢獻(xiàn)的主題。適當(dāng)?shù)闹黝}包括但不限于重要疾病和疾病載體的潛在病理生理學(xué);各種疾病的治療方法;目的研究藥物分子靶點(diǎn)的性質(zhì)。促進(jìn)尋找治療方法的重要新方法;基因組學(xué)和蛋白質(zhì)組學(xué);藥物系列的構(gòu)效關(guān)系開發(fā)新的成像和診斷工具;藥物代謝;藥物輸送;化學(xué)藥物的藥代動(dòng)力學(xué)、藥效學(xué)和臨床特點(diǎn)的重要性。評(píng)論主要由編輯征求意見(jiàn);不過(guò)，也鼓勵(lì)自愿捐款。在后一種情況下，潛在的作者被要求在開始寫作前與合作編輯中的任何一位聯(lián)系提綱，以避免重復(fù)工作，并確保主題及其報(bào)道水平的適宜性。

The journal publishes timely critical reviews of topics related to medicinal research broadly defined to which the authors have made significant contributions. Appropriate topics include but are not limited to the underlying pathophysiology of important diseases and disease vectors; therapeutic approaches to the treatment of various diseases; the properties of molecular targets for therapeutic agents; important new methodologies facilitating the search for therapies; genomics and proteomics; structure-activity correlations of drug series; the development of new imaging and diagnostic tools; drug metabolism; drug delivery; chemical pharmacological pharmacokinetic pharmacodynamic and clinical characteristics of importance. Reviews are mainly solicited by the editors; however voluntary contributions are also encouraged. In the latter case potential authors are asked to contact either co-editor with an outline before beginning to write in order to avoid duplication of effort and to ensure suitability of the topic and its level of coverage.