《美國生理學雜志:內分泌學與代謝》發表了有關內分泌與代謝系統的任何組織水平的原始研究成果。將考慮對整個動物或人類進行分子、亞細胞和細胞研究。具體主題包括激素和生長因子的作用機制；激素或代謝產物對有機和無機代謝的控制；對內分泌細胞表現的旁分泌和自分泌控制；基因表達的激活；激素受體的功能和激活；離子通道和膜功能的內分泌或代謝控制；內分泌和生殖細胞功能的分化；激素分泌和代謝的時間分析；激素作用或代謝的數學模型和動力學分析。對激素作用或受體激活的新分子、免疫學、磁共振或電生理學研究也是受歡迎的。

The American Journal of Physiology: Endocrinology and Metabolism publishes results of original studies about endocrine and metabolic systems on any level of organization. Molecular, subcellular, and cellular studies in whole animals or humans will be considered. Specific themes include mechanisms of hormone and growth factor action; hormonal or metabolite control of organic and inorganic metabolism; paracrine and autocrine control of endocrine cell performance; activation of gene expression; function and activation of hormone receptors; endocrine or metabolic control of ion channels and membrane function; differentiation of endocrine and reproductive cell function; temporal analysis of hormone secretion and metabolism; and mathematical modeling and kinetic analysis of hormone action or metabolism. Novel molecular, immunological, magnetic resonance, or electrophysiological studies of hormone action or receptor activation are also welcome.