《微生物學波譜》發表受委托撰寫的評論文章，內容涉及微生物學的十個領域:古菌;食品微生物學;細菌遺傳學、細胞生物學和生理學;臨床微生物學;環境微生物學與生態學;真核微生物;基因組學、計算學和合成微生物學;免疫學;發病機理;和病毒學。評審是相互關聯的，每個評審都鏈接到其他相關內容。一個大型的微生物學光譜編輯委員會幫助開發潛在評論的主題，并確定一個或多個編輯，誰負責管理每個收集。文章由各個領域的主要研究人員撰寫并進行同行評審。雖然評審是委托進行的，微生物學光譜不接受非應邀的文章，但歡迎提出專題意見建議。微生物學光譜在PubMed、Scopus、新興資源引文索引(Web of Science)、CAS、AGRICOLA以及CAB摘要和全球健康數據庫中都有索引。

Microbiology Spectrum publishes commissioned review articles on topics in microbiology representing ten content areas: Archaea; Food Microbiology; Bacterial Genetics, Cell Biology, and Physiology; Clinical Microbiology; Environmental Microbiology and Ecology; Eukaryotic Microbes; Genomics, Computational, and Synthetic Microbiology; Immunology; Pathogenesis; and Virology. Reviews are interrelated, with each review linking to other related content. A large board of Microbiology Spectrum editors aids in the development of topics for potential reviews and in the identification of an editor, or editors, who shepherd each collection. Articles are written and peer-reviewed by leading researchers in each field. Although the reviews are commissioned and Microbiology Spectrum does not accept unsolicited articles, topical idea suggestions are welcomed. Microbiology Spectrum is indexed in PubMed, Scopus, Emerging Sources Citation Index (Web of Science), CAS, AGRICOLA, and the CAB Abstracts and Global Health database.